Amlodipine besylate; benazepril hydrochloride
TL;DR: Amlodipine besylate; benazepril hydrochloride (CAS 858669-53-1) is a chemical compound with molecular formula C50H60Cl2N4O13S and molecular weight 1026.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
benzenesulfonic acid;2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
Also Known As: Lotrel, Amlobenz, AMOLDIPINE BENAZEPRIL HCL, Amlodipine besylate and benazepril hydrochloride, AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE
| Molecular Formula | C50H60Cl2N4O13S |
|---|---|
| Molecular Weight | 1026.33 g/mol |
| LogP | 6.1945 |
| Topological Polar Surface Area | 250.19 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 18 |
| Exact Mass | 1026.3254 |
| Heavy Atoms | 70 |
| Complexity | 2563.0012 |
Chemical Identifiers
| CAS Number | 858669-53-1 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O.C1=CC=C(C=C1)S(=O)(=O)O.Cl |
Product Overview
Amlodipine besylate; benazepril hydrochloride (CAS 858669-53-1), with molecular formula C50H60Cl2N4O13S and molecular weight 1026.33 g/mol. IUPAC: benzenesulfonic acid;2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride.
Chemical Property Profile of Amlodipine besylate; benazepril hydrochloride
Property Insights of Amlodipine besylate; benazepril hydrochloride
The XLogP value of 6.1945 indicates that Amlodipine besylate; benazepril hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 250.19 Ų indicates high polarity, suggesting Amlodipine besylate; benazepril hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amlodipine besylate; benazepril hydrochloride has 5 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amlodipine besylate; benazepril hydrochloride?
The CAS number of Amlodipine besylate; benazepril hydrochloride is 858669-53-1.
What is the molecular formula of Amlodipine besylate; benazepril hydrochloride?
The molecular formula of Amlodipine besylate; benazepril hydrochloride is C50H60Cl2N4O13S.
What is the molecular weight of Amlodipine besylate; benazepril hydrochloride?
The molecular weight of Amlodipine besylate; benazepril hydrochloride is 1026.33 g/mol.
Where can I buy Amlodipine besylate; benazepril hydrochloride?
You can request a quote for Amlodipine besylate; benazepril hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amlodipine besylate; benazepril hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Amlodipine besylate; benazepril hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.