1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one
TL;DR: 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one (CAS 85732-32-7) is a chemical compound with molecular formula C21H25N3O2 and molecular weight 351.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1'-(2-hydroxy-2-phenylethyl)-3-methylspiro[1H-quinazoline-4,4'-piperidine]-2-one
Also Known As: 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one, 1'-(2-Phenyl-2-hydroxyethyl)-(3-methyl-3,4-dihydro-2(1H)-quinzolinone-4-spiro-4'-piperidine), Spiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one, 1-(2-hydroxy-2-phenylethyl)-3'-methyl-, 1'-(2-hydroxy-2-phenylethyl)-3-methylspiro[1H-quinazoline-4,4'-piperidine]-2-one, 1-(2-Hydroxy-2-phenylethyl)-3'-methyl-3'H-spiro[piperidine-4,4'-quinazolin]-2'-ol
| Molecular Formula | C21H25N3O2 |
|---|---|
| Molecular Weight | 351.19 g/mol |
| LogP | 3.1886 |
| Topological Polar Surface Area | 55.81 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 351.19467 |
| Heavy Atoms | 26 |
| Complexity | 784.853 |
Chemical Identifiers
| CAS Number | 85732-32-7 |
|---|---|
| SMILES | CN1C(=O)NC2=CC=CC=C2C13CCN(CC3)CC(C4=CC=CC=C4)O |
Product Overview
1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one (CAS 85732-32-7), with molecular formula C21H25N3O2 and molecular weight 351.19 g/mol. IUPAC: 1'-(2-hydroxy-2-phenylethyl)-3-methylspiro[1H-quinazoline-4,4'-piperidine]-2-one.
Chemical Property Profile of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one
Property Insights of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one
The XLogP value of 3.1886 indicates that 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.81 Ų, 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one?
The CAS number of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one is 85732-32-7.
What is the molecular formula of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one?
The molecular formula of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one is C21H25N3O2.
What is the molecular weight of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one?
The molecular weight of 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one is 351.19 g/mol.
Where can I buy 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one?
You can request a quote for 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-Hydroxy-2-phenylethyl)-3'-methylspiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.