NHS-Biotin
TL;DR: NHS-Biotin (CAS 85718-04-3) is a chemical compound with molecular formula C14H19N3O5S and molecular weight 341.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2,5-dioxopyrrolidin-1-yl) 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoate
Also Known As: NHS-Biotin, Biotin-OSu, Biotin-NHS, NHS-Biotin(98% ), (+)-Biotin N-hydroxysuccinimide ester
| Molecular Formula | C14H19N3O5S |
|---|---|
| Molecular Weight | 341.10 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 130.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 341.10455 |
| Heavy Atoms | 23 |
| Complexity | 525.0 |
Chemical Identifiers
| CAS Number | 85718-04-3 |
|---|---|
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3 |
| InChIKey | YMXHPSHLTSZXKH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
NHS-Biotin (CAS 85718-04-3), with molecular formula C14H19N3O5S and molecular weight 341.10 g/mol. IUPAC: (2,5-dioxopyrrolidin-1-yl) 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoate.
Chemical Property Profile of NHS-Biotin
Property Insights of NHS-Biotin
The XLogP value of -0.2 indicates that NHS-Biotin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 130.0 Ų falls within the moderate polarity range, balancing permeability and solubility for NHS-Biotin. Following Lipinski's Rule of Five, NHS-Biotin has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NHS-Biotin?
The CAS number of NHS-Biotin is 85718-04-3.
What is the molecular formula of NHS-Biotin?
The molecular formula of NHS-Biotin is C14H19N3O5S.
What is the molecular weight of NHS-Biotin?
The molecular weight of NHS-Biotin is 341.10 g/mol.
Where can I buy NHS-Biotin?
You can request a quote for NHS-Biotin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NHS-Biotin?
Yes, KEHONG BIO provides custom synthesis services for NHS-Biotin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.