Cediranib
TL;DR: Cediranib (CAS 857036-77-2) is a chemical compound with molecular formula C25H27FN4O3 and molecular weight 450.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
Also Known As: Cediranib, Recentin, Cedirannib, cediranibum, Chelocardin
| Molecular Formula | C25H27FN4O3 |
|---|---|
| Molecular Weight | 450.21 g/mol |
| LogP | 5.22422 |
| Topological Polar Surface Area | 72.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 450.20673 |
| Heavy Atoms | 33 |
| Complexity | 1283.8633 |
Chemical Identifiers
| CAS Number | 857036-77-2 |
|---|---|
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5 |
Product Overview
Cediranib (CAS 857036-77-2), with molecular formula C25H27FN4O3 and molecular weight 450.21 g/mol. IUPAC: 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
Chemical Property Profile of Cediranib
Property Insights of Cediranib
The XLogP value of 5.22422 indicates that Cediranib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Cediranib. Following Lipinski's Rule of Five, Cediranib has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cediranib?
The CAS number of Cediranib is 857036-77-2.
What is the molecular formula of Cediranib?
The molecular formula of Cediranib is C25H27FN4O3.
What is the molecular weight of Cediranib?
The molecular weight of Cediranib is 450.21 g/mol.
Where can I buy Cediranib?
You can request a quote for Cediranib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cediranib?
Yes, KEHONG BIO provides custom synthesis services for Cediranib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.