Nicardipine Impurity 18
TL;DR: Nicardipine Impurity 18 (CAS 85677-95-8) is a chemical compound with molecular formula C18H20N2O7 and molecular weight 376.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-(2-hydroxyethyl) 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Nicardipine Impurity 18, Nimodipine Impurity 11, Nicardipine Impurity 17, 2-hydroxyethyl Methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3-(2-HYDROXYETHYL) 5-METHYL 2,6-DIMETHYL-4-(3-NITROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE
| Molecular Formula | C18H20N2O7 |
|---|---|
| Molecular Weight | 376.13 g/mol |
| LogP | 1.5381 |
| Topological Polar Surface Area | 128.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 376.12704 |
| Heavy Atoms | 27 |
| Complexity | 841.8668 |
Chemical Identifiers
| CAS Number | 85677-95-8 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCCO)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC |
Product Overview
Nicardipine Impurity 18 (CAS 85677-95-8), with molecular formula C18H20N2O7 and molecular weight 376.13 g/mol. IUPAC: 5-O-(2-hydroxyethyl) 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Nicardipine Impurity 18
Property Insights of Nicardipine Impurity 18
The XLogP value of 1.5381 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nicardipine Impurity 18. The TPSA of 128.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nicardipine Impurity 18. Following Lipinski's Rule of Five, Nicardipine Impurity 18 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nicardipine Impurity 18?
The CAS number of Nicardipine Impurity 18 is 85677-95-8.
What is the molecular formula of Nicardipine Impurity 18?
The molecular formula of Nicardipine Impurity 18 is C18H20N2O7.
What is the molecular weight of Nicardipine Impurity 18?
The molecular weight of Nicardipine Impurity 18 is 376.13 g/mol.
Where can I buy Nicardipine Impurity 18?
You can request a quote for Nicardipine Impurity 18 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nicardipine Impurity 18?
Yes, KEHONG BIO provides custom synthesis services for Nicardipine Impurity 18 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.