Dehydro nimodipine structure

Dehydro nimodipine

TL;DR: Dehydro nimodipine (CAS 85677-93-6) is a chemical compound with molecular formula C21H24N2O7 and molecular weight 416.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-O-(2-methoxyethyl) 3-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Also Known As: Dehydro nimodipine, Nimodipine EP Impurity A, Nimodipine M (dehydro), Nimodipine Impurity A, Nimodipine related compound A

CAS: 85677-93-6
Molecular Formula C21H24N2O7
Molecular Weight 416.16 g/mol
LogP 3.5
Topological Polar Surface Area 121.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 9
Exact Mass 416.15836
Heavy Atoms 30
Complexity 607.0

Chemical Identifiers

CAS Number 85677-93-6
SMILES CC1=C(C(=C(C(=N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
InChIKey SJJUCKCPGPCJQM-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (13 patents) Pharmaceutical Intermediates (15 patents)

Product Overview

Dehydro nimodipine (CAS 85677-93-6), with molecular formula C21H24N2O7 and molecular weight 416.16 g/mol. IUPAC: 5-O-(2-methoxyethyl) 3-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dehydro nimodipine

XLogP
3.5
TPSA (Topological Polar Surface Area)
121.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
9
Heavy Atoms
30
Complexity
607.0
Exact Mass
416.15836
Monoisotopic Mass
416.15836
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dehydro nimodipine

The XLogP value of 3.5 indicates that Dehydro nimodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 121.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Dehydro nimodipine. Following Lipinski's Rule of Five, Dehydro nimodipine has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dehydro nimodipine?

The CAS number of Dehydro nimodipine is 85677-93-6.

What is the molecular formula of Dehydro nimodipine?

The molecular formula of Dehydro nimodipine is C21H24N2O7.

What is the molecular weight of Dehydro nimodipine?

The molecular weight of Dehydro nimodipine is 416.16 g/mol.

Where can I buy Dehydro nimodipine?

You can request a quote for Dehydro nimodipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dehydro nimodipine?

Yes, KEHONG BIO provides custom synthesis services for Dehydro nimodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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