PL 385 structure

PL 385

TL;DR: PL 385 (CAS 85550-66-9) is a chemical compound with molecular formula C29H30N8O8S and molecular weight 650.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S,5R,6R)-6-[[2-[[2-(4-formylpiperazin-1-yl)-5-oxo-8H-pyrido[2,3-d]pyrimidine-6-carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Also Known As: PL 385, (S)-1-(Trityloxy)-2-propanol, (2S,5R,6R)-6-[[2-[[2-(4-formylpiperazin-1-yl)-5-oxo-8H-pyrido[2,3-d]pyrimidine-6-carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((((2-(4-formyl-1-piperazinyl)-1,5-dihydro-5-oxopyrido(2,3-d)pyrimidin-6-yl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, Sodium 6-(2-(2-(4-formyl-1-piperazinyl)-5,8-dihydro-5-oxopyrido-(2,3)pyrimidine-6-carboxamido)-4-hydroxyphenylacetamido)-penicillanate

CAS: 85550-66-9
Molecular Formula C29H30N8O8S
Molecular Weight 650.19 g/mol
LogP -0.5951
Topological Polar Surface Area 218.23 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 11
Rotatable Bonds 8
Exact Mass 650.19073
Heavy Atoms 46
Complexity 1806.9127

Chemical Identifiers

CAS Number 85550-66-9
SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(C3=CC=C(C=C3)O)NC(=O)C4=CNC5=NC(=NC=C5C4=O)N6CCN(CC6)C=O)C(=O)O)C

Product Overview

PL 385 (CAS 85550-66-9), with molecular formula C29H30N8O8S and molecular weight 650.19 g/mol. IUPAC: (2S,5R,6R)-6-[[2-[[2-(4-formylpiperazin-1-yl)-5-oxo-8H-pyrido[2,3-d]pyrimidine-6-carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PL 385

XLogP
-0.5951
TPSA (Topological Polar Surface Area)
218.23
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
11
Rotatable Bonds
8
Heavy Atoms
46
Complexity
1806.9127
Exact Mass
650.19073
Monoisotopic Mass
650.19073
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PL 385

The XLogP value of -0.5951 indicates that PL 385 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 218.23 Ų indicates high polarity, suggesting PL 385 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, PL 385 has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PL 385?

The CAS number of PL 385 is 85550-66-9.

What is the molecular formula of PL 385?

The molecular formula of PL 385 is C29H30N8O8S.

What is the molecular weight of PL 385?

The molecular weight of PL 385 is 650.19 g/mol.

Where can I buy PL 385?

You can request a quote for PL 385 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PL 385?

Yes, KEHONG BIO provides custom synthesis services for PL 385 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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