Pyroglutamyl-glutamyl-proline amide
TL;DR: Pyroglutamyl-glutamyl-proline amide (CAS 85541-78-2) is a chemical compound with molecular formula C15H22N4O6 and molecular weight 354.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S)-5-[(2S)-2-carbamoylpyrrolidin-1-yl]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid
Also Known As: (Glu2)-TRH, Pglu-glu-pronh2, Pglu-glu-pro-amide, Glp-glu-pronh2, PYR-GLU-PRO-NH2
| Molecular Formula | C15H22N4O6 |
|---|---|
| Molecular Weight | 354.15 g/mol |
| LogP | -2.7 |
| Topological Polar Surface Area | 159.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 354.15393 |
| Heavy Atoms | 25 |
| Complexity | 593.0 |
Chemical Identifiers
| CAS Number | 85541-78-2 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]2CCC(=O)N2)C(=O)N |
| InChIKey | HYZBGWLLSXSYLX-GUBZILKMSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Pyroglutamyl-glutamyl-proline amide (CAS 85541-78-2), with molecular formula C15H22N4O6 and molecular weight 354.15 g/mol. IUPAC: (4S)-5-[(2S)-2-carbamoylpyrrolidin-1-yl]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid.
Chemical Property Profile of Pyroglutamyl-glutamyl-proline amide
Property Insights of Pyroglutamyl-glutamyl-proline amide
The XLogP value of -2.7 indicates that Pyroglutamyl-glutamyl-proline amide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 159.0 Ų indicates high polarity, suggesting Pyroglutamyl-glutamyl-proline amide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-glutamyl-proline amide has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-glutamyl-proline amide?
The CAS number of Pyroglutamyl-glutamyl-proline amide is 85541-78-2.
What is the molecular formula of Pyroglutamyl-glutamyl-proline amide?
The molecular formula of Pyroglutamyl-glutamyl-proline amide is C15H22N4O6.
What is the molecular weight of Pyroglutamyl-glutamyl-proline amide?
The molecular weight of Pyroglutamyl-glutamyl-proline amide is 354.15 g/mol.
Where can I buy Pyroglutamyl-glutamyl-proline amide?
You can request a quote for Pyroglutamyl-glutamyl-proline amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-glutamyl-proline amide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-glutamyl-proline amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.