4-(5-Chloro-2-thienyl)-2-pyrimidinamine
TL;DR: 4-(5-Chloro-2-thienyl)-2-pyrimidinamine (CAS 855308-65-5) is a chemical compound with molecular formula C8H6ClN3S and molecular weight 211.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(5-chlorothiophen-2-yl)pyrimidin-2-amine
Also Known As: 4-(5-chlorothiophen-2-yl)pyrimidin-2-amine, 4-(5-chloro-2-thienyl)-2-pyrimidinamine, 4- -2-PYRIMIDINAMINE, 0785AF, 4-(5-chloro-2-thienyl)pyrimidin-2-amine
| Molecular Formula | C8H6ClN3S |
|---|---|
| Molecular Weight | 211.00 g/mol |
| LogP | 2.4407 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 210.9971 |
| Heavy Atoms | 13 |
| Complexity | 426.83243 |
Chemical Identifiers
| CAS Number | 855308-65-5 |
|---|---|
| SMILES | C1=CN=C(N=C1C2=CC=C(S2)Cl)N |
Product Overview
4-(5-Chloro-2-thienyl)-2-pyrimidinamine (CAS 855308-65-5), with molecular formula C8H6ClN3S and molecular weight 211.00 g/mol. IUPAC: 4-(5-chlorothiophen-2-yl)pyrimidin-2-amine.
Chemical Property Profile of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine
Property Insights of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine
The XLogP value of 2.4407 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(5-Chloro-2-thienyl)-2-pyrimidinamine. With a topological polar surface area (TPSA) of 51.8 Ų, 4-(5-Chloro-2-thienyl)-2-pyrimidinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(5-Chloro-2-thienyl)-2-pyrimidinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine?
The CAS number of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine is 855308-65-5.
What is the molecular formula of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine?
The molecular formula of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine is C8H6ClN3S.
What is the molecular weight of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine?
The molecular weight of 4-(5-Chloro-2-thienyl)-2-pyrimidinamine is 211.00 g/mol.
Where can I buy 4-(5-Chloro-2-thienyl)-2-pyrimidinamine?
You can request a quote for 4-(5-Chloro-2-thienyl)-2-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(5-Chloro-2-thienyl)-2-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-(5-Chloro-2-thienyl)-2-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.