Thyrotropin-releasing hormone, gly
TL;DR: Thyrotropin-releasing hormone, gly (CAS 85344-77-0) is a chemical compound with molecular formula C18H24N6O6 and molecular weight 420.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
Also Known As: Trh-gly, Pglu-his-pro-gly, Trh, gly, Pglu-his-pro-glyoh, TRH-glycine
| Molecular Formula | C18H24N6O6 |
|---|---|
| Molecular Weight | 420.18 g/mol |
| LogP | -2.5 |
| Topological Polar Surface Area | 174.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 420.17572 |
| Heavy Atoms | 30 |
| Complexity | 715.0 |
Chemical Identifiers
| CAS Number | 85344-77-0 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)NCC(=O)O |
| InChIKey | CSVCLHYFVGHUCM-AVGNSLFASA-N |
Product Overview
Thyrotropin-releasing hormone, gly (CAS 85344-77-0), with molecular formula C18H24N6O6 and molecular weight 420.18 g/mol. IUPAC: 2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid.
Chemical Property Profile of Thyrotropin-releasing hormone, gly
Property Insights of Thyrotropin-releasing hormone, gly
The XLogP value of -2.5 indicates that Thyrotropin-releasing hormone, gly is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 174.0 Ų indicates high polarity, suggesting Thyrotropin-releasing hormone, gly may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thyrotropin-releasing hormone, gly has 5 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thyrotropin-releasing hormone, gly?
The CAS number of Thyrotropin-releasing hormone, gly is 85344-77-0.
What is the molecular formula of Thyrotropin-releasing hormone, gly?
The molecular formula of Thyrotropin-releasing hormone, gly is C18H24N6O6.
What is the molecular weight of Thyrotropin-releasing hormone, gly?
The molecular weight of Thyrotropin-releasing hormone, gly is 420.18 g/mol.
Where can I buy Thyrotropin-releasing hormone, gly?
You can request a quote for Thyrotropin-releasing hormone, gly directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thyrotropin-releasing hormone, gly?
Yes, KEHONG BIO provides custom synthesis services for Thyrotropin-releasing hormone, gly and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.