(2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide
TL;DR: (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide (CAS 853348-56-8) is a chemical compound with molecular formula C14H12ClNOS and molecular weight 277.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(3-chloro-2-methylphenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: N-(3-chloro-2-methylphenyl)-3-(2-thienyl)acrylamide, n-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide, (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide, (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)prop-2-enamide, (2E)-N-(3-chloro-2-methylphenyl)-3-(thiophen-2-yl)prop-2-enamide
| Molecular Formula | C14H12ClNOS |
|---|---|
| Molecular Weight | 277.03 g/mol |
| LogP | 4.36182 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 277.0328 |
| Heavy Atoms | 18 |
| Complexity | 575.48486 |
Chemical Identifiers
| CAS Number | 853348-56-8 |
|---|---|
| SMILES | CC1=C(C=CC=C1Cl)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
(2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide (CAS 853348-56-8), with molecular formula C14H12ClNOS and molecular weight 277.03 g/mol. IUPAC: (E)-N-(3-chloro-2-methylphenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide
Property Insights of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide
The XLogP value of 4.36182 indicates that (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide?
The CAS number of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide is 853348-56-8.
What is the molecular formula of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide?
The molecular formula of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide is C14H12ClNOS.
What is the molecular weight of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide?
The molecular weight of (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide is 277.03 g/mol.
Where can I buy (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide?
You can request a quote for (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-(3-chloro-2-methylphenyl)-3-(2-thienyl)-2-propenamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.