(2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide
TL;DR: (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide (CAS 853347-87-2) is a chemical compound with molecular formula C14H12ClNO2S and molecular weight 293.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(5-chloro-2-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: IDI1_007080, AB00712785-01, n-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide, (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide, (E)-N-(5-chloro-2-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide
| Molecular Formula | C14H12ClNO2S |
|---|---|
| Molecular Weight | 293.03 g/mol |
| LogP | 4.062 |
| Topological Polar Surface Area | 38.33 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 293.02774 |
| Heavy Atoms | 19 |
| Complexity | 593.49835 |
Chemical Identifiers
| CAS Number | 853347-87-2 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
(2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide (CAS 853347-87-2), with molecular formula C14H12ClNO2S and molecular weight 293.03 g/mol. IUPAC: (E)-N-(5-chloro-2-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide
Property Insights of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide
The XLogP value of 4.062 indicates that (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.33 Ų, (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide?
The CAS number of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide is 853347-87-2.
What is the molecular formula of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide?
The molecular formula of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide is C14H12ClNO2S.
What is the molecular weight of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide?
The molecular weight of (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide is 293.03 g/mol.
Where can I buy (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide?
You can request a quote for (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-(5-chloro-2-methoxyphenyl)-3-(2-thienyl)-2-propenamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.