3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide
TL;DR: 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide (CAS 853347-85-0) is a chemical compound with molecular formula C14H10F3NOS and molecular weight 297.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-thiophen-2-yl-N-[3-(trifluoromethyl)phenyl]prop-2-enamide
Also Known As: 3-(2-THIENYL)-N-(3-(TRIFLUOROMETHYL)PHENYL)-2-PROPENAMIDE, AB00710168-01, (2E)-3-(2-thienyl)-N-[3-(trifluoromethyl)phenyl]prop-2-enamide, (E)-3-thiophen-2-yl-N-[3-(trifluoromethyl)phenyl]prop-2-enamide, (2E)-3-(thiophen-2-yl)-N-[3-(trifluoromethyl)phenyl]prop-2-enamide
| Molecular Formula | C14H10F3NOS |
|---|---|
| Molecular Weight | 297.04 g/mol |
| LogP | 4.4188 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 297.04352 |
| Heavy Atoms | 20 |
| Complexity | 617.5993 |
Chemical Identifiers
| CAS Number | 853347-85-0 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=O)/C=C/C2=CC=CS2)C(F)(F)F |
Product Overview
3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide (CAS 853347-85-0), with molecular formula C14H10F3NOS and molecular weight 297.04 g/mol. IUPAC: (E)-3-thiophen-2-yl-N-[3-(trifluoromethyl)phenyl]prop-2-enamide.
Chemical Property Profile of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide
Property Insights of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide
The XLogP value of 4.4188 indicates that 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide?
The CAS number of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide is 853347-85-0.
What is the molecular formula of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide?
The molecular formula of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide is C14H10F3NOS.
What is the molecular weight of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide?
The molecular weight of 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide is 297.04 g/mol.
Where can I buy 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide?
You can request a quote for 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide?
Yes, KEHONG BIO provides custom synthesis services for 3-(2-Thienyl)-N-(3-(trifluoromethyl)phenyl)-2-propenamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.