![2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one structure](/static/products/852/852389-12-9.png)
2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one
TL;DR: 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one (CAS 852389-12-9) is a chemical compound with molecular formula C11H13ClN2O2S and molecular weight 272.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone
Also Known As: 2-chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one, 1-(chloroacetyl)-4-(thien-2-ylcarbonyl)piperazine, UPCMLD0ENAT5342281:001, 2-chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone
| Molecular Formula | C11H13ClN2O2S |
|---|---|
| Molecular Weight | 272.04 g/mol |
| LogP | 1.2713 |
| Topological Polar Surface Area | 40.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 272.03864 |
| Heavy Atoms | 17 |
| Complexity | 399.61374 |
Chemical Identifiers
| CAS Number | 852389-12-9 |
|---|---|
| SMILES | C1CN(CCN1C(=O)CCl)C(=O)C2=CC=CS2 |
Product Overview
2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one (CAS 852389-12-9), with molecular formula C11H13ClN2O2S and molecular weight 272.04 g/mol. IUPAC: 2-chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone.
Chemical Property Profile of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one
Property Insights of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one
The XLogP value of 1.2713 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one. With a topological polar surface area (TPSA) of 40.62 Ų, 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one?
The CAS number of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one is 852389-12-9.
What is the molecular formula of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one?
The molecular formula of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one is C11H13ClN2O2S.
What is the molecular weight of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one?
The molecular weight of 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one is 272.04 g/mol.
Where can I buy 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one?
You can request a quote for 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-1-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.