F0676-0362 structure

F0676-0362

TL;DR: F0676-0362 (CAS 852374-45-9) is a chemical compound with molecular formula C18H18FN5OS and molecular weight 371.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl]-1-piperidin-1-ylethanone

Also Known As: F0676-0362, 2-((3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-1-(piperidin-1-yl)ethanone, 2-{[3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl}-1-(piperidin-1-yl)ethan-1-one, 2-[[3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl]-1-piperidin-1-ylethanone, 2-[3-(m-fluorophenyl)-1,2,3a,4-tetraaza-5-indenylthio]-1-piperidino-1-ethanone

CAS: 852374-45-9
Molecular Formula C18H18FN5OS
Molecular Weight 371.12 g/mol
LogP 3.035
Topological Polar Surface Area 63.39 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 371.1216
Heavy Atoms 26
Complexity 938.2311

Chemical Identifiers

CAS Number 852374-45-9
SMILES C1CCN(CC1)C(=O)CSC2=NN3C(=NN=C3C4=CC(=CC=C4)F)C=C2

Product Overview

F0676-0362 (CAS 852374-45-9), with molecular formula C18H18FN5OS and molecular weight 371.12 g/mol. IUPAC: 2-[[3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl]-1-piperidin-1-ylethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0676-0362

XLogP
3.035
TPSA (Topological Polar Surface Area)
63.39
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
26
Complexity
938.2311
Exact Mass
371.1216
Monoisotopic Mass
371.1216
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0676-0362

The XLogP value of 3.035 indicates that F0676-0362 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.39 Ų falls within the moderate polarity range, balancing permeability and solubility for F0676-0362. Following Lipinski's Rule of Five, F0676-0362 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0676-0362?

The CAS number of F0676-0362 is 852374-45-9.

What is the molecular formula of F0676-0362?

The molecular formula of F0676-0362 is C18H18FN5OS.

What is the molecular weight of F0676-0362?

The molecular weight of F0676-0362 is 371.12 g/mol.

Where can I buy F0676-0362?

You can request a quote for F0676-0362 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0676-0362?

Yes, KEHONG BIO provides custom synthesis services for F0676-0362 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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