(2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide
TL;DR: (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide (CAS 852028-46-7) is a chemical compound with molecular formula C13H9N3OS and molecular weight 255.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-pyridin-2-yl-3-thiophen-2-ylprop-2-enamide
Also Known As: (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide, (E)-2-cyano-N-pyridin-2-yl-3-thiophen-2-ylprop-2-enamide, 2-cyano-N-pyridin-2-yl-3-thiophen-2-yl-prop-2-enamide, (E)-2-cyano-N-(2-pyridyl)-3-(2-thienyl)prop-2-enamide, (2E)-2-cyano-N-(pyridin-2-yl)-3-(thiophen-2-yl)prop-2-enamide
| Molecular Formula | C13H9N3OS |
|---|---|
| Molecular Weight | 255.05 g/mol |
| LogP | 2.68878 |
| Topological Polar Surface Area | 65.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 255.04663 |
| Heavy Atoms | 18 |
| Complexity | 596.9215 |
Chemical Identifiers
| CAS Number | 852028-46-7 |
|---|---|
| SMILES | C1=CC=NC(=C1)NC(=O)/C(=C/C2=CC=CS2)/C#N |
Product Overview
(2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide (CAS 852028-46-7), with molecular formula C13H9N3OS and molecular weight 255.05 g/mol. IUPAC: (E)-2-cyano-N-pyridin-2-yl-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide
Property Insights of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide
The XLogP value of 2.68878 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide. The TPSA of 65.78 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide. Following Lipinski's Rule of Five, (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide?
The CAS number of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide is 852028-46-7.
What is the molecular formula of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide?
The molecular formula of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide is C13H9N3OS.
What is the molecular weight of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide?
The molecular weight of (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide is 255.05 g/mol.
Where can I buy (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide?
You can request a quote for (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-cyano-N-pyridin-2-yl-3-(2-thienyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.