F0636-0345
TL;DR: F0636-0345 (CAS 851945-90-9) is a chemical compound with molecular formula C15H9ClF3N3O2S and molecular weight 387.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
Also Known As: F0636-0345, N-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, N-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide, N-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, N-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-4-oxo-1-thia-3a,7-diaza-5-indenecarboxamide
| Molecular Formula | C15H9ClF3N3O2S |
|---|---|
| Molecular Weight | 387.01 g/mol |
| LogP | 3.98892 |
| Topological Polar Surface Area | 63.47 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 387.0056 |
| Heavy Atoms | 25 |
| Complexity | 1042.6581 |
Chemical Identifiers
| CAS Number | 851945-90-9 |
|---|---|
| SMILES | CC1=CSC2=NC=C(C(=O)N12)C(=O)NC3=C(C=CC(=C3)C(F)(F)F)Cl |
Product Overview
F0636-0345 (CAS 851945-90-9), with molecular formula C15H9ClF3N3O2S and molecular weight 387.01 g/mol. IUPAC: N-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide.
Chemical Property Profile of F0636-0345
Property Insights of F0636-0345
The XLogP value of 3.98892 indicates that F0636-0345 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.47 Ų falls within the moderate polarity range, balancing permeability and solubility for F0636-0345. Following Lipinski's Rule of Five, F0636-0345 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0636-0345?
The CAS number of F0636-0345 is 851945-90-9.
What is the molecular formula of F0636-0345?
The molecular formula of F0636-0345 is C15H9ClF3N3O2S.
What is the molecular weight of F0636-0345?
The molecular weight of F0636-0345 is 387.01 g/mol.
Where can I buy F0636-0345?
You can request a quote for F0636-0345 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0636-0345?
Yes, KEHONG BIO provides custom synthesis services for F0636-0345 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.