![N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine structure](/static/products/851/851903-11-2.png)
N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
TL;DR: N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 851903-11-2) is a chemical compound with molecular formula C22H22BrF3N4OS and molecular weight 526.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-bromo-3-(trifluoromethyl)phenyl]-2-(morpholin-4-ylmethyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-amine
Also Known As: N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine, N-[4-bromo-3-(trifluoromethyl)phenyl]-2-(morpholin-4-ylmethyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-amine
| Molecular Formula | C22H22BrF3N4OS |
|---|---|
| Molecular Weight | 526.07 g/mol |
| LogP | 5.9272 |
| Topological Polar Surface Area | 50.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 526.065 |
| Heavy Atoms | 32 |
| Complexity | 1144.3868 |
Chemical Identifiers
| CAS Number | 851903-11-2 |
|---|---|
| SMILES | C1CCC2=C(C1)C3=C(N=C(N=C3S2)CN4CCOCC4)NC5=CC(=C(C=C5)Br)C(F)(F)F |
Product Overview
N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 851903-11-2), with molecular formula C22H22BrF3N4OS and molecular weight 526.07 g/mol. IUPAC: N-[4-bromo-3-(trifluoromethyl)phenyl]-2-(morpholin-4-ylmethyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-amine.
Chemical Property Profile of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
Property Insights of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
The XLogP value of 5.9272 indicates that N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.28 Ų, N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine?
The CAS number of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine is 851903-11-2.
What is the molecular formula of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine?
The molecular formula of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine is C22H22BrF3N4OS.
What is the molecular weight of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine?
The molecular weight of N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine is 526.07 g/mol.
Where can I buy N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine?
You can request a quote for N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for N-(4-Bromo-3-(trifluoromethyl)phenyl)-2-(morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.