![2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide structure](/static/products/851/851817-79-3.png)
2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
TL;DR: 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide (CAS 851817-79-3) is a chemical compound with molecular formula C17H18F3N5O and molecular weight 365.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
Also Known As: 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide, 2-[4-(pyrimidin-2-yl)piperazin-1-yl]-N-[2-(trifluoromethyl)phenyl]acetamide, 2-(4-pyrimidin-2-ylpiperazinyl)-N-[2-(trifluoromethyl)phenyl]acetamide, 2-[4-(2-pyrimidinyl)-1-piperazinyl]-N-[2-(trifluoromethyl)phenyl]acetamide
| Molecular Formula | C17H18F3N5O |
|---|---|
| Molecular Weight | 365.15 g/mol |
| LogP | 2.2561 |
| Topological Polar Surface Area | 61.36 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 365.14633 |
| Heavy Atoms | 26 |
| Complexity | 745.5636 |
Chemical Identifiers
| CAS Number | 851817-79-3 |
|---|---|
| SMILES | C1CN(CCN1CC(=O)NC2=CC=CC=C2C(F)(F)F)C3=NC=CC=N3 |
Product Overview
2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide (CAS 851817-79-3), with molecular formula C17H18F3N5O and molecular weight 365.15 g/mol. IUPAC: 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide.
Chemical Property Profile of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
Property Insights of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
The XLogP value of 2.2561 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide. The TPSA of 61.36 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide. Following Lipinski's Rule of Five, 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide?
The CAS number of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide is 851817-79-3.
What is the molecular formula of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide?
The molecular formula of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide is C17H18F3N5O.
What is the molecular weight of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide?
The molecular weight of 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide is 365.15 g/mol.
Where can I buy 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide?
You can request a quote for 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-pyrimidin-2-ylpiperazin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.