F0631-0254 structure

F0631-0254

TL;DR: F0631-0254 (CAS 851810-75-8) is a chemical compound with molecular formula C18H22FN5OS and molecular weight 375.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[(4-ethylpiperazin-1-yl)-(4-fluorophenyl)methyl]-2-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol

Also Known As: F0631-0254, 5-((4-ethylpiperazin-1-yl)(4-fluorophenyl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[(4-ethylpiperazin-1-yl)(4-fluorophenyl)methyl]-2-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-[(4-ethylpiperazin-1-yl)-(4-fluorophenyl)methyl]-2-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol

CAS: 851810-75-8
Molecular Formula C18H22FN5OS
Molecular Weight 375.15 g/mol
LogP 2.67082
Topological Polar Surface Area 56.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 375.15292
Heavy Atoms 26
Complexity 898.3373

Chemical Identifiers

CAS Number 851810-75-8
SMILES CCN1CCN(CC1)C(C2=CC=C(C=C2)F)C3=C(N4C(=NC(=N4)C)S3)O

Product Overview

F0631-0254 (CAS 851810-75-8), with molecular formula C18H22FN5OS and molecular weight 375.15 g/mol. IUPAC: 5-[(4-ethylpiperazin-1-yl)-(4-fluorophenyl)methyl]-2-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F0631-0254

XLogP
2.67082
TPSA (Topological Polar Surface Area)
56.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
26
Complexity
898.3373
Exact Mass
375.15292
Monoisotopic Mass
375.15292
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0631-0254

The XLogP value of 2.67082 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F0631-0254. With a topological polar surface area (TPSA) of 56.9 Ų, F0631-0254 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0631-0254 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0631-0254?

The CAS number of F0631-0254 is 851810-75-8.

What is the molecular formula of F0631-0254?

The molecular formula of F0631-0254 is C18H22FN5OS.

What is the molecular weight of F0631-0254?

The molecular weight of F0631-0254 is 375.15 g/mol.

Where can I buy F0631-0254?

You can request a quote for F0631-0254 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0631-0254?

Yes, KEHONG BIO provides custom synthesis services for F0631-0254 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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