(Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
TL;DR: (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one (CAS 851429-36-2) is a chemical compound with molecular formula C15H17N3OS and molecular weight 287.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
Also Known As: 1H-Pyrazole,5-methyl-1-octyl-3-phenyl, Monosubstituted aryl-Me ATX inhibitor 1, (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one, F0444-0036, (5Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
| Molecular Formula | C15H17N3OS |
|---|---|
| Molecular Weight | 287.11 g/mol |
| LogP | 1.9043 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 287.10922 |
| Heavy Atoms | 20 |
| Complexity | 559.74115 |
Chemical Identifiers
| CAS Number | 851429-36-2 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC(=O)/C(=C/C3=CC=CC=C3)/S2 |
Product Overview
(Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one (CAS 851429-36-2), with molecular formula C15H17N3OS and molecular weight 287.11 g/mol. IUPAC: (5Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one.
Chemical Property Profile of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
Property Insights of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one
The XLogP value of 1.9043 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one. With a topological polar surface area (TPSA) of 35.91 Ų, (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The CAS number of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is 851429-36-2.
What is the molecular formula of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The molecular formula of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is C15H17N3OS.
What is the molecular weight of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
The molecular weight of (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one is 287.11 g/mol.
Where can I buy (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
You can request a quote for (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-5-benzylidene-2-(4-methylpiperazin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.