![(E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole structure](/static/products/849/849918-63-4.png)
(E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole
TL;DR: (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole (CAS 849918-63-4) is a chemical compound with molecular formula C25H27N5 and molecular weight 397.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,8-dimethyl-4-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]pyrimido[5,4-b]indole
Also Known As: (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole, 5,8-dimethyl-4-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]pyrimido[5,4-b]indole, 5,8-dimethyl-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole
| Molecular Formula | C25H27N5 |
|---|---|
| Molecular Weight | 397.23 g/mol |
| LogP | 4.26532 |
| Topological Polar Surface Area | 37.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 397.22665 |
| Heavy Atoms | 30 |
| Complexity | 1200.6548 |
Chemical Identifiers
| CAS Number | 849918-63-4 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)N(C3=C2N=CN=C3N4CCN(CC4)C/C=C/C5=CC=CC=C5)C |
Product Overview
(E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole (CAS 849918-63-4), with molecular formula C25H27N5 and molecular weight 397.23 g/mol. IUPAC: 5,8-dimethyl-4-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]pyrimido[5,4-b]indole.
Chemical Property Profile of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole
Property Insights of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole
The XLogP value of 4.26532 indicates that (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.19 Ų, (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole?
The CAS number of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole is 849918-63-4.
What is the molecular formula of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole?
The molecular formula of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole is C25H27N5.
What is the molecular weight of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole?
The molecular weight of (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole is 397.23 g/mol.
Where can I buy (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole?
You can request a quote for (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole?
Yes, KEHONG BIO provides custom synthesis services for (E)-4-(4-cinnamylpiperazin-1-yl)-5,8-dimethyl-5H-pyrimido[5,4-b]indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.