PKZ18
TL;DR: PKZ18 (CAS 849658-87-3) is a chemical compound with molecular formula C22H26N2O3S and molecular weight 398.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,2R,3S,4R)-3-[[5-methyl-4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
Also Known As: PKZ18, PKZ 18, EX-A5823, (1S,2R,3S,4R)-3-[[5-methyl-4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid, (1R,2S,3R,4S)-rel-3-[[[5-methyl-4-[4-(1-methylethyl)phenyl]-2-thiazolyl]amino]carbonyl]-bicyclo[2.2.1]heptane-2-carboxylic acid
| Molecular Formula | C22H26N2O3S |
|---|---|
| Molecular Weight | 398.17 g/mol |
| LogP | 4.92732 |
| Topological Polar Surface Area | 79.29 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 398.1664 |
| Heavy Atoms | 28 |
| Complexity | 903.00574 |
Chemical Identifiers
| CAS Number | 849658-87-3 |
|---|---|
| SMILES | CC1=C(N=C(S1)NC(=O)[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)O)C4=CC=C(C=C4)C(C)C |
Product Overview
PKZ18 (CAS 849658-87-3), with molecular formula C22H26N2O3S and molecular weight 398.17 g/mol. IUPAC: (1S,2R,3S,4R)-3-[[5-methyl-4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid.
Chemical Property Profile of PKZ18
Property Insights of PKZ18
The XLogP value of 4.92732 indicates that PKZ18 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.29 Ų falls within the moderate polarity range, balancing permeability and solubility for PKZ18. Following Lipinski's Rule of Five, PKZ18 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of PKZ18?
The CAS number of PKZ18 is 849658-87-3.
What is the molecular formula of PKZ18?
The molecular formula of PKZ18 is C22H26N2O3S.
What is the molecular weight of PKZ18?
The molecular weight of PKZ18 is 398.17 g/mol.
Where can I buy PKZ18?
You can request a quote for PKZ18 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for PKZ18?
Yes, KEHONG BIO provides custom synthesis services for PKZ18 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.