L-2'-deoxy-2'-fluoro-5-ethynyluridine
TL;DR: L-2'-deoxy-2'-fluoro-5-ethynyluridine (CAS 849342-90-1) is a chemical compound with molecular formula C11H11FN2O5 and molecular weight 270.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-ethynyl-1-[(2S,3S,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: L-2'-deoxy-2'-fluoro-5-ethynyluridine, Uridine, L-2'-deoxy-2'-fluoro-5-ethynyl-, 1-(2'-Deoxy-2'-fluoro-.beta.-L-ribofuranosyl)-5-ethynyl-uracil, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-, A-L-ribofuranosyl)-5-ethynyl-
| Molecular Formula | C11H11FN2O5 |
|---|---|
| Molecular Weight | 270.07 g/mol |
| LogP | -1.8934 |
| Topological Polar Surface Area | 104.55 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 270.0652 |
| Heavy Atoms | 19 |
| Complexity | 631.1983 |
Chemical Identifiers
| CAS Number | 849342-90-1 |
|---|---|
| SMILES | C#CC1=CN(C(=O)NC1=O)[C@@H]2[C@H]([C@H]([C@@H](O2)CO)O)F |
Product Overview
L-2'-deoxy-2'-fluoro-5-ethynyluridine (CAS 849342-90-1), with molecular formula C11H11FN2O5 and molecular weight 270.07 g/mol. IUPAC: 5-ethynyl-1-[(2S,3S,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of L-2'-deoxy-2'-fluoro-5-ethynyluridine
Property Insights of L-2'-deoxy-2'-fluoro-5-ethynyluridine
The XLogP value of -1.8934 indicates that L-2'-deoxy-2'-fluoro-5-ethynyluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.55 Ų falls within the moderate polarity range, balancing permeability and solubility for L-2'-deoxy-2'-fluoro-5-ethynyluridine. Following Lipinski's Rule of Five, L-2'-deoxy-2'-fluoro-5-ethynyluridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-2'-deoxy-2'-fluoro-5-ethynyluridine?
The CAS number of L-2'-deoxy-2'-fluoro-5-ethynyluridine is 849342-90-1.
What is the molecular formula of L-2'-deoxy-2'-fluoro-5-ethynyluridine?
The molecular formula of L-2'-deoxy-2'-fluoro-5-ethynyluridine is C11H11FN2O5.
What is the molecular weight of L-2'-deoxy-2'-fluoro-5-ethynyluridine?
The molecular weight of L-2'-deoxy-2'-fluoro-5-ethynyluridine is 270.07 g/mol.
Where can I buy L-2'-deoxy-2'-fluoro-5-ethynyluridine?
You can request a quote for L-2'-deoxy-2'-fluoro-5-ethynyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-2'-deoxy-2'-fluoro-5-ethynyluridine?
Yes, KEHONG BIO provides custom synthesis services for L-2'-deoxy-2'-fluoro-5-ethynyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.