Deacetyl-O-demethyldiltiazem structure

Deacetyl-O-demethyldiltiazem

TL;DR: Deacetyl-O-demethyldiltiazem (CAS 84903-82-2) is a chemical compound with molecular formula C19H22N2O3S and molecular weight 358.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one

Also Known As: Deacetyl-O-demethyldiltiazem, O-Demethyldeacetyldiltiazem, 5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one, 5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one, 5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5h)-one

CAS: 84903-82-2
Molecular Formula C19H22N2O3S
Molecular Weight 358.14 g/mol
LogP 2.2
Topological Polar Surface Area 89.3 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 358.1351
Heavy Atoms 25
Complexity 454.0

Chemical Identifiers

CAS Number 84903-82-2
SMILES CN(C)CCN1C2=CC=CC=C2SC(C(C1=O)O)C3=CC=C(C=C3)O
InChIKey QYKYTLTVPBXRNC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (4 patents) Pharmaceutical Intermediates (8 patents)

Product Overview

Deacetyl-O-demethyldiltiazem (CAS 84903-82-2), with molecular formula C19H22N2O3S and molecular weight 358.14 g/mol. IUPAC: 5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Deacetyl-O-demethyldiltiazem

XLogP
2.2
TPSA (Topological Polar Surface Area)
89.3
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
25
Complexity
454.0
Exact Mass
358.1351
Monoisotopic Mass
358.1351
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Deacetyl-O-demethyldiltiazem

The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Deacetyl-O-demethyldiltiazem. The TPSA of 89.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Deacetyl-O-demethyldiltiazem. Following Lipinski's Rule of Five, Deacetyl-O-demethyldiltiazem has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Deacetyl-O-demethyldiltiazem?

The CAS number of Deacetyl-O-demethyldiltiazem is 84903-82-2.

What is the molecular formula of Deacetyl-O-demethyldiltiazem?

The molecular formula of Deacetyl-O-demethyldiltiazem is C19H22N2O3S.

What is the molecular weight of Deacetyl-O-demethyldiltiazem?

The molecular weight of Deacetyl-O-demethyldiltiazem is 358.14 g/mol.

Where can I buy Deacetyl-O-demethyldiltiazem?

You can request a quote for Deacetyl-O-demethyldiltiazem directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Deacetyl-O-demethyldiltiazem?

Yes, KEHONG BIO provides custom synthesis services for Deacetyl-O-demethyldiltiazem and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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