F1727-0181
TL;DR: F1727-0181 (CAS 849007-59-6) is a chemical compound with molecular formula C26H26ClN5 and molecular weight 443.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(2-chlorophenyl)methyl]-1-(4-ethylpiperazin-1-yl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
Also Known As: F1727-0181, 2-(2-chlorobenzyl)-1-(4-ethylpiperazin-1-yl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile, 12-[(2-chlorophenyl)methyl]-13-(4-ethylpiperazin-1-yl)-11-methyl-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8,10,12-hexaene-10-carbonitrile, 2-(2-chlorobenzyl)-1-(4-ethylpiperazin-1-yl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile, 2-[(2-chlorophenyl)methyl]-1-(4-ethylpiperazin-1-yl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
| Molecular Formula | C26H26ClN5 |
|---|---|
| Molecular Weight | 443.19 g/mol |
| LogP | 5.0537 |
| Topological Polar Surface Area | 47.57 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 443.18768 |
| Heavy Atoms | 32 |
| Complexity | 1342.086 |
Chemical Identifiers
| CAS Number | 849007-59-6 |
|---|---|
| SMILES | CCN1CCN(CC1)C2=C(C(=C(C3=NC4=CC=CC=C4N23)C#N)C)CC5=CC=CC=C5Cl |
Product Overview
F1727-0181 (CAS 849007-59-6), with molecular formula C26H26ClN5 and molecular weight 443.19 g/mol. IUPAC: 2-[(2-chlorophenyl)methyl]-1-(4-ethylpiperazin-1-yl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile.
Chemical Property Profile of F1727-0181
Property Insights of F1727-0181
The XLogP value of 5.0537 indicates that F1727-0181 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.57 Ų, F1727-0181 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1727-0181 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1727-0181?
The CAS number of F1727-0181 is 849007-59-6.
What is the molecular formula of F1727-0181?
The molecular formula of F1727-0181 is C26H26ClN5.
What is the molecular weight of F1727-0181?
The molecular weight of F1727-0181 is 443.19 g/mol.
Where can I buy F1727-0181?
You can request a quote for F1727-0181 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1727-0181?
Yes, KEHONG BIO provides custom synthesis services for F1727-0181 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.