![7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione structure](/static/products/849/849006-59-3.png)
7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione
TL;DR: 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione (CAS 849006-59-3) is a chemical compound with molecular formula C22H23N3OS and molecular weight 377.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7,7-dimethyl-2-(4-methylphenyl)-1-(pyridin-3-ylmethyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione
Also Known As: 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione, 7,7-Dimethyl-1-pyridin-3-ylmethyl-2-p-tolyl-1,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidine-4-thione, 7,7-dimethyl-2-(4-methylphenyl)-1-(pyridin-3-ylmethyl)-1,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidine-4-thione, 7,7-dimethyl-2-(4-methylphenyl)-1-(pyridin-3-ylmethyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione
| Molecular Formula | C22H23N3OS |
|---|---|
| Molecular Weight | 377.16 g/mol |
| LogP | 4.88261 |
| Topological Polar Surface Area | 39.94 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 377.1562 |
| Heavy Atoms | 27 |
| Complexity | 1023.9187 |
Chemical Identifiers
| CAS Number | 849006-59-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC(=S)C3=C(N2CC4=CN=CC=C4)CC(OC3)(C)C |
Product Overview
7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione (CAS 849006-59-3), with molecular formula C22H23N3OS and molecular weight 377.16 g/mol. IUPAC: 7,7-dimethyl-2-(4-methylphenyl)-1-(pyridin-3-ylmethyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione.
Chemical Property Profile of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione
Property Insights of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione
The XLogP value of 4.88261 indicates that 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.94 Ų, 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione?
The CAS number of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione is 849006-59-3.
What is the molecular formula of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione?
The molecular formula of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione is C22H23N3OS.
What is the molecular weight of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione?
The molecular weight of 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione is 377.16 g/mol.
Where can I buy 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione?
You can request a quote for 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 7,7-dimethyl-1-(pyridin-3-ylmethyl)-2-(p-tolyl)-7,8-dihydro-1H-pyrano[4,3-d]pyrimidine-4(5H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.