![(5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one structure](/static/products/849/849002-06-8.png)
(5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one
TL;DR: (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one (CAS 849002-06-8) is a chemical compound with molecular formula C26H22F3N3O2S and molecular weight 497.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-1,3-thiazol-4-one
Also Known As: (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one, (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-1,3-thiazol-4-one, (E)-2-(4-(o-tolyl)piperazin-1-yl)-5-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)thiazol-4(5H)-one
| Molecular Formula | C26H22F3N3O2S |
|---|---|
| Molecular Weight | 497.14 g/mol |
| LogP | 6.06632 |
| Topological Polar Surface Area | 49.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 497.1385 |
| Heavy Atoms | 35 |
| Complexity | 1321.1262 |
Chemical Identifiers
| CAS Number | 849002-06-8 |
|---|---|
| SMILES | CC1=CC=CC=C1N2CCN(CC2)C3=NC(=O)/C(=C\C4=CC=C(O4)C5=CC(=CC=C5)C(F)(F)F)/S3 |
Product Overview
(5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one (CAS 849002-06-8), with molecular formula C26H22F3N3O2S and molecular weight 497.14 g/mol. IUPAC: (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one
Property Insights of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one
The XLogP value of 6.06632 indicates that (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.05 Ų, (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one?
The CAS number of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one is 849002-06-8.
What is the molecular formula of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one?
The molecular formula of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one is C26H22F3N3O2S.
What is the molecular weight of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one?
The molecular weight of (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one is 497.14 g/mol.
Where can I buy (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one?
You can request a quote for (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-2-[4-(2-methylphenyl)piperazin-1-yl]-5-({5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.