![(5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one structure](/static/products/848/848923-55-7.png)
(5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one
TL;DR: (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one (CAS 848923-55-7) is a chemical compound with molecular formula C25H19F4N3O2S and molecular weight 501.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one, (5Z)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one, (Z)-5-((5-(4-fluorophenyl)furan-2-yl)methylene)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)thiazol-4(5H)-one
| Molecular Formula | C25H19F4N3O2S |
|---|---|
| Molecular Weight | 501.11 g/mol |
| LogP | 5.897 |
| Topological Polar Surface Area | 49.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 501.1134 |
| Heavy Atoms | 35 |
| Complexity | 1306.7462 |
Chemical Identifiers
| CAS Number | 848923-55-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC(=C2)C(F)(F)F)C3=NC(=O)/C(=C/C4=CC=C(O4)C5=CC=C(C=C5)F)/S3 |
Product Overview
(5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one (CAS 848923-55-7), with molecular formula C25H19F4N3O2S and molecular weight 501.11 g/mol. IUPAC: (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one
Property Insights of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one
The XLogP value of 5.897 indicates that (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.05 Ų, (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one?
The CAS number of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one is 848923-55-7.
What is the molecular formula of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one?
The molecular formula of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one is C25H19F4N3O2S.
What is the molecular weight of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one?
The molecular weight of (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one is 501.11 g/mol.
Where can I buy (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one?
You can request a quote for (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.