(E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one
TL;DR: (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one (CAS 848736-41-4) is a chemical compound with molecular formula C20H21N3O2S and molecular weight 367.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[[5-(4-methylphenyl)furan-2-yl]methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
Also Known As: (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one, 5-[[5-(4-methylphenyl)-2-furyl]methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one, (5E)-5-[[5-(4-methylphenyl)furan-2-yl]methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one, (5E)-5-{[5-(4-methylphenyl)furan-2-yl]methylidene}-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one
| Molecular Formula | C20H21N3O2S |
|---|---|
| Molecular Weight | 367.14 g/mol |
| LogP | 3.47272 |
| Topological Polar Surface Area | 49.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 367.13544 |
| Heavy Atoms | 26 |
| Complexity | 874.7162 |
Chemical Identifiers
| CAS Number | 848736-41-4 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=CC=C(O2)/C=C/3\C(=O)N=C(S3)N4CCN(CC4)C |
Product Overview
(E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one (CAS 848736-41-4), with molecular formula C20H21N3O2S and molecular weight 367.14 g/mol. IUPAC: (5E)-5-[[5-(4-methylphenyl)furan-2-yl]methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one.
Chemical Property Profile of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one
Property Insights of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one
The XLogP value of 3.47272 indicates that (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.05 Ų, (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one?
The CAS number of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one is 848736-41-4.
What is the molecular formula of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one?
The molecular formula of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one is C20H21N3O2S.
What is the molecular weight of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one?
The molecular weight of (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one is 367.14 g/mol.
Where can I buy (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one?
You can request a quote for (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-methylpiperazin-1-yl)-5-((5-(p-tolyl)furan-2-yl)methylene)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.