![(E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide structure](/static/products/848/848681-17-4.png)
(E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide
TL;DR: (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide (CAS 848681-17-4) is a chemical compound with molecular formula C24H20N6O3 and molecular weight 440.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[5-cyano-11-methyl-2-oxo-7-(oxolan-2-ylmethyl)-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaen-6-ylidene]pyridine-3-carboxamide
Also Known As: (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide, N-[(2E)-3-cyano-10-methyl-5-oxo-1-(tetrahydrofuran-2-ylmethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]pyridine-3-carboxamide, N-[3-cyano-10-methyl-5-oxidanylidene-1-(oxolan-2-ylmethyl)dipyrido[3,4-c:1'',2''-f]pyrimidin-2-ylidene]pyridine-3-carboxamide, N-[3-cyano-10-methyl-5-oxo-1-(2-oxolanylmethyl)-2-dipyrido[3,4-c:1'',2''-f]pyrimidinylidene]-3-pyridinecarboxamide, N-[3-cyano-10-methyl-5-oxo-1-(oxolan-2-ylmethyl)dipyrido[3,4-c:1'',2''-f]pyrimidin-2-ylidene]pyridine-3-carboxamide
| Molecular Formula | C24H20N6O3 |
|---|---|
| Molecular Weight | 440.16 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 111.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 440.1597 |
| Heavy Atoms | 33 |
| Complexity | 1130.0 |
Chemical Identifiers
| CAS Number | 848681-17-4 |
|---|---|
| SMILES | CC1=CC=CN2C1=NC3=C(C2=O)C=C(C(=NC(=O)C4=CN=CC=C4)N3CC5CCCO5)C#N |
| InChIKey | IEZPKQRQIUHFHV-UHFFFAOYSA-N |
Product Overview
(E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide (CAS 848681-17-4), with molecular formula C24H20N6O3 and molecular weight 440.16 g/mol. IUPAC: N-[5-cyano-11-methyl-2-oxo-7-(oxolan-2-ylmethyl)-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaen-6-ylidene]pyridine-3-carboxamide.
Chemical Property Profile of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide
Property Insights of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide. The TPSA of 111.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide. Following Lipinski's Rule of Five, (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide?
The CAS number of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide is 848681-17-4.
What is the molecular formula of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide?
The molecular formula of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide is C24H20N6O3.
What is the molecular weight of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide?
The molecular weight of (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide is 440.16 g/mol.
Where can I buy (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide?
You can request a quote for (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(3-cyano-10-methyl-5-oxo-1-((tetrahydrofuran-2-yl)methyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-2(5H)-ylidene)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.