![12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one structure](/static/products/848/848674-38-4.png)
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one
概要：12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one（CAS 848674-38-4）是一种化学化合物，分子式为C28H26N4O5，分子量为498.19 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
9-(3,4-dimethoxyphenyl)-13-(2-hydroxyphenyl)-5,5-dimethyl-2-oxa-12,14,15,17-tetrazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),11,13,16-pentaen-7-one
又称：12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one, 12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-9,10-dihydro-8H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11(12H)-one
| 分子式 | C28H26N4O5 |
|---|---|
| 分子量 | 498.19 g/mol |
| LogP | 4.6816 |
| 拓扑极性表面积 | 108.07 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 8 |
| 可旋转键数 | 4 |
| 精确质量 | 498.1903 |
| 重原子数 | 37 |
| 复杂度 | 1603.6681 |
化学标识符
| CAS 编号 | 848674-38-4 |
|---|---|
| SMILES | CC1(CC2=C(C(C3=C(O2)N=CN4C3=NC(=N4)C5=CC=CC=C5O)C6=CC(=C(C=C6)OC)OC)C(=O)C1)C |
产品概述
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one（CAS 848674-38-4），分子式为C28H26N4O5，分子量为498.19 g/mol。IUPAC名：9-(3,4-dimethoxyphenyl)-13-(2-hydroxyphenyl)-5,5-dimethyl-2-oxa-12,14,15,17-tetrazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),11,13,16-pentaen-7-one。
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one化学性质概览
属性洞察：12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的XLogP值为4.6816，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为108.07 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one有1个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的CAS号是多少？
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的CAS号为848674-38-4。
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的分子式是什么？
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的分子式为C28H26N4O5。
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的分子量是多少？
12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的分子量为498.19 g/mol。
在哪里可以购买12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one？
您可以直接向科弘生物询价12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one的定制合成服务？
是的，科弘生物提供12-(3,4-dimethoxyphenyl)-2-(2-hydroxyphenyl)-9,9-dimethyl-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。