![12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE structure](/static/products/848/848669-90-9.png)
12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE
TL;DR: 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE (CAS 848669-90-9) is a chemical compound with molecular formula C27H25N5O4 and molecular weight 483.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
9-(3,4-dimethoxyphenyl)-5,5-dimethyl-13-pyridin-3-yl-2-oxa-12,14,15,17-tetrazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),11,13,16-pentaen-7-one
Also Known As: 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE, 12-(3,4-dimethoxyphenyl)-9,9-dimethyl-2-(pyridin-3-yl)-8,9,10,12-tetrahydro-11H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11-one, 12-(3,4-dimethoxyphenyl)-9,9-dimethyl-2-(pyridin-3-yl)-9,10-dihydro-8H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11(12H)-one
| Molecular Formula | C27H25N5O4 |
|---|---|
| Molecular Weight | 483.19 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 483.19064 |
| Heavy Atoms | 36 |
| Complexity | 880.0 |
Chemical Identifiers
| CAS Number | 848669-90-9 |
|---|---|
| SMILES | CC1(CC2=C(C(C3=C(O2)N=CN4C3=NC(=N4)C5=CN=CC=C5)C6=CC(=C(C=C6)OC)OC)C(=O)C1)C |
| InChIKey | ILHLLVFRUXNPDJ-UHFFFAOYSA-N |
Product Overview
12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE (CAS 848669-90-9), with molecular formula C27H25N5O4 and molecular weight 483.19 g/mol. IUPAC: 9-(3,4-dimethoxyphenyl)-5,5-dimethyl-13-pyridin-3-yl-2-oxa-12,14,15,17-tetrazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),11,13,16-pentaen-7-one.
Chemical Property Profile of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE
Property Insights of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE
The XLogP value of 3.5 indicates that 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE. Following Lipinski's Rule of Five, 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE?
The CAS number of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE is 848669-90-9.
What is the molecular formula of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE?
The molecular formula of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE is C27H25N5O4.
What is the molecular weight of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE?
The molecular weight of 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE is 483.19 g/mol.
Where can I buy 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE?
You can request a quote for 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE?
Yes, KEHONG BIO provides custom synthesis services for 12-(3,4-DIMETHOXYPHENYL)-9,9-DIMETHYL-2-(3-PYRIDYL)-8,9,10,12-TETRAHYDRO-11H-CHROMENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-11-ONE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.