![rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/848/848436-26-0.png)
rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 848436-26-0) is a chemical compound with molecular formula C23H23F3N4O4 and molecular weight 476.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S,7R)-N-(2,4-dimethoxyphenyl)-5-(3-methoxyphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, (5S,7R)-N-(2,4-dimethoxyphenyl)-5-(3-methoxyphenyl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C23H23F3N4O4 |
|---|---|
| Molecular Weight | 476.17 g/mol |
| LogP | 4.8215 |
| Topological Polar Surface Area | 86.64 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 476.16714 |
| Heavy Atoms | 34 |
| Complexity | 1195.1986 |
Chemical Identifiers
| CAS Number | 848436-26-0 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)NC(=O)C2=C3N[C@@H](C[C@@H](N3N=C2)C(F)(F)F)C4=CC(=CC=C4)OC)OC |
Product Overview
rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 848436-26-0), with molecular formula C23H23F3N4O4 and molecular weight 476.17 g/mol. IUPAC: (5S,7R)-N-(2,4-dimethoxyphenyl)-5-(3-methoxyphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 4.8215 indicates that rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.64 Ų falls within the moderate polarity range, balancing permeability and solubility for rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 848436-26-0.
What is the molecular formula of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is C23H23F3N4O4.
What is the molecular weight of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is 476.17 g/mol.
Where can I buy rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for rel-(5R,7S)-N-(2,4-Dimethoxyphenyl)-4,5,6,7-tetrahydro-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.