C12H4Cl2F3N3OS
TL;DR: C12H4Cl2F3N3OS (CAS 848422-66-2) is a chemical compound with molecular formula C12H4Cl2F3N3OS and molecular weight 364.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
Also Known As: 3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 3-Chloro-5-thiophen-2-yl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 3-Chloro-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonylchloride, 3-Chloro-5-thien-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
| Molecular Formula | C12H4Cl2F3N3OS |
|---|---|
| Molecular Weight | 364.94 g/mol |
| LogP | 4.509 |
| Topological Polar Surface Area | 47.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.94043 |
| Heavy Atoms | 22 |
| Complexity | 873.9944 |
Chemical Identifiers
| CAS Number | 848422-66-2 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NC3=C(C(=NN3C(=C2)C(F)(F)F)C(=O)Cl)Cl |
Product Overview
C12H4Cl2F3N3OS (CAS 848422-66-2), with molecular formula C12H4Cl2F3N3OS and molecular weight 364.94 g/mol. IUPAC: 3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride.
Chemical Property Profile of C12H4Cl2F3N3OS
Property Insights of C12H4Cl2F3N3OS
The XLogP value of 4.509 indicates that C12H4Cl2F3N3OS is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.26 Ų, C12H4Cl2F3N3OS exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, C12H4Cl2F3N3OS has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of C12H4Cl2F3N3OS?
The CAS number of C12H4Cl2F3N3OS is 848422-66-2.
What is the molecular formula of C12H4Cl2F3N3OS?
The molecular formula of C12H4Cl2F3N3OS is C12H4Cl2F3N3OS.
What is the molecular weight of C12H4Cl2F3N3OS?
The molecular weight of C12H4Cl2F3N3OS is 364.94 g/mol.
Where can I buy C12H4Cl2F3N3OS?
You can request a quote for C12H4Cl2F3N3OS directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for C12H4Cl2F3N3OS?
Yes, KEHONG BIO provides custom synthesis services for C12H4Cl2F3N3OS and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.