(E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide
TL;DR: (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 847367-05-9) is a chemical compound with molecular formula C15H11ClF3N3O2S and molecular weight 389.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-[(E)-1-(5-chlorothiophen-2-yl)ethylideneamino]-N-[3-(trifluoromethyl)phenyl]oxamide
Also Known As: (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide, 2-{(2E)-2-[1-(5-chlorothiophen-2-yl)ethylidene]hydrazinyl}-2-oxo-N-[3-(trifluoromethyl)phenyl]acetamide, 2-{N'-[1-(5-Chloro-thiophen-2-yl)-eth-(E)-ylidene]-hydrazino}-2-oxo-N-(3-trifluoromethyl-phenyl)-acetami de
| Molecular Formula | C15H11ClF3N3O2S |
|---|---|
| Molecular Weight | 389.02 g/mol |
| LogP | 3.8992 |
| Topological Polar Surface Area | 70.56 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 389.02127 |
| Heavy Atoms | 25 |
| Complexity | 833.42426 |
Chemical Identifiers
| CAS Number | 847367-05-9 |
|---|---|
| SMILES | C/C(=N\NC(=O)C(=O)NC1=CC=CC(=C1)C(F)(F)F)/C2=CC=C(S2)Cl |
Product Overview
(E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 847367-05-9), with molecular formula C15H11ClF3N3O2S and molecular weight 389.02 g/mol. IUPAC: N'-[(E)-1-(5-chlorothiophen-2-yl)ethylideneamino]-N-[3-(trifluoromethyl)phenyl]oxamide.
Chemical Property Profile of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide
Property Insights of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide
The XLogP value of 3.8992 indicates that (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.56 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide. Following Lipinski's Rule of Five, (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide?
The CAS number of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide is 847367-05-9.
What is the molecular formula of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide?
The molecular formula of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide is C15H11ClF3N3O2S.
What is the molecular weight of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide?
The molecular weight of (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide is 389.02 g/mol.
Where can I buy (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide?
You can request a quote for (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(2-(1-(5-chlorothiophen-2-yl)ethylidene)hydrazinyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.