![(E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one structure](/static/products/847/847246-55-3.png)
(E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
TL;DR: (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 847246-55-3) is a chemical compound with molecular formula C22H14FN3O2S and molecular weight 403.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-(2H-chromen-3-ylmethylidene)-2-[(E)-2-(4-fluorophenyl)ethenyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
Also Known As: (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one, (5E)-5-(2H-chromen-3-ylmethylidene)-2-[(E)-2-(4-fluorophenyl)ethenyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
| Molecular Formula | C22H14FN3O2S |
|---|---|
| Molecular Weight | 403.08 g/mol |
| LogP | 3.4359 |
| Topological Polar Surface Area | 56.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 403.07907 |
| Heavy Atoms | 29 |
| Complexity | 1383.9491 |
Chemical Identifiers
| CAS Number | 847246-55-3 |
|---|---|
| SMILES | C1C(=CC2=CC=CC=C2O1)/C=C/3\C(=O)N4C(=NC(=N4)/C=C/C5=CC=C(C=C5)F)S3 |
Product Overview
(E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 847246-55-3), with molecular formula C22H14FN3O2S and molecular weight 403.08 g/mol. IUPAC: (5E)-5-(2H-chromen-3-ylmethylidene)-2-[(E)-2-(4-fluorophenyl)ethenyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one.
Chemical Property Profile of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
Property Insights of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
The XLogP value of 3.4359 indicates that (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.49 Ų, (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one?
The CAS number of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is 847246-55-3.
What is the molecular formula of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one?
The molecular formula of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is C22H14FN3O2S.
What is the molecular weight of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one?
The molecular weight of (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is 403.08 g/mol.
Where can I buy (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one?
You can request a quote for (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-5-((2H-chromen-3-yl)methylene)-2-((E)-4-fluorostyryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.