Tris(hydroxymethyl)aminomethane succinate structure

Tris(hydroxymethyl)aminomethane succinate

TL;DR: Tris(hydroxymethyl)aminomethane succinate (CAS 84540-64-7) is a chemical compound with molecular formula C12H28N2O10 and molecular weight 360.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

bis(2-amino-2-(hydroxymethyl)propane-1,3-diol);butanedioic acid

Also Known As: Tris succinate, Trizma succinate, Trizmasuccinate, Trizma(R) succinate, Trizma® succinate

CAS: 84540-64-7
Molecular Formula C12H28N2O10
Molecular Weight 360.17 g/mol
LogP -4.7426
Topological Polar Surface Area 248.02 Ų
Hydrogen Bond Donors 10
Hydrogen Bond Acceptors 10
Rotatable Bonds 9
Exact Mass 360.1744
Heavy Atoms 24
Complexity 283.27094

Chemical Identifiers

CAS Number 84540-64-7
SMILES C(CC(=O)O)C(=O)O.C(C(CO)(CO)N)O.C(C(CO)(CO)N)O

Product Overview

Tris(hydroxymethyl)aminomethane succinate (CAS 84540-64-7), with molecular formula C12H28N2O10 and molecular weight 360.17 g/mol. IUPAC: bis(2-amino-2-(hydroxymethyl)propane-1,3-diol);butanedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tris(hydroxymethyl)aminomethane succinate

XLogP
-4.7426
TPSA (Topological Polar Surface Area)
248.02
Hydrogen Bond Donors
10
Hydrogen Bond Acceptors
10
Rotatable Bonds
9
Heavy Atoms
24
Complexity
283.27094
Exact Mass
360.1744
Monoisotopic Mass
360.1744
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tris(hydroxymethyl)aminomethane succinate

The XLogP value of -4.7426 indicates that Tris(hydroxymethyl)aminomethane succinate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 248.02 Ų indicates high polarity, suggesting Tris(hydroxymethyl)aminomethane succinate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tris(hydroxymethyl)aminomethane succinate has 10 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tris(hydroxymethyl)aminomethane succinate?

The CAS number of Tris(hydroxymethyl)aminomethane succinate is 84540-64-7.

What is the molecular formula of Tris(hydroxymethyl)aminomethane succinate?

The molecular formula of Tris(hydroxymethyl)aminomethane succinate is C12H28N2O10.

What is the molecular weight of Tris(hydroxymethyl)aminomethane succinate?

The molecular weight of Tris(hydroxymethyl)aminomethane succinate is 360.17 g/mol.

Where can I buy Tris(hydroxymethyl)aminomethane succinate?

You can request a quote for Tris(hydroxymethyl)aminomethane succinate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tris(hydroxymethyl)aminomethane succinate?

Yes, KEHONG BIO provides custom synthesis services for Tris(hydroxymethyl)aminomethane succinate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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