Sibutramine Hydrochloride
TL;DR: Sibutramine Hydrochloride (CAS 84485-00-7) is a chemical compound with molecular formula C17H27Cl2N and molecular weight 315.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine;hydrochloride
Also Known As: Sibutramine hydrochloride, SIBUTRAMINE HCl, Meridia, Reductil, Yeduc
| Molecular Formula | C17H27Cl2N |
|---|---|
| Molecular Weight | 315.15 g/mol |
| LogP | 5.16 |
| Topological Polar Surface Area | 3.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 315.15207 |
| Heavy Atoms | 20 |
| Complexity | 275.0 |
| Solubility | <0.7 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 84485-00-7 |
|---|---|
| SMILES | CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C.Cl |
| InChIKey | UWAOJIWUVCMBAZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Sibutramine Hydrochloride (CAS 84485-00-7), with molecular formula C17H27Cl2N and molecular weight 315.15 g/mol. IUPAC: 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine;hydrochloride.
Chemical Property Profile of Sibutramine Hydrochloride
Property Insights of Sibutramine Hydrochloride
The XLogP value of 5.16 indicates that Sibutramine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Sibutramine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sibutramine Hydrochloride has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sibutramine Hydrochloride?
The CAS number of Sibutramine Hydrochloride is 84485-00-7.
What is the molecular formula of Sibutramine Hydrochloride?
The molecular formula of Sibutramine Hydrochloride is C17H27Cl2N.
What is the molecular weight of Sibutramine Hydrochloride?
The molecular weight of Sibutramine Hydrochloride is 315.15 g/mol.
Where can I buy Sibutramine Hydrochloride?
You can request a quote for Sibutramine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sibutramine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Sibutramine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.