1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
TL;DR: 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one (CAS 844649-61-2) is a chemical compound with molecular formula C12H10Cl2N2O2 and molecular weight 284.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2,6-dichlorophenyl)methyl]-5-methylpyrimidine-2,4-dione
Also Known As: 1-[(2,6-dichlorophenyl)methyl]-5-methylpyrimidine-2,4-dione, 1-(2,6-dichlorobenzyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
| Molecular Formula | C12H10Cl2N2O2 |
|---|---|
| Molecular Weight | 284.01 g/mol |
| LogP | 2.20012 |
| Topological Polar Surface Area | 54.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 284.01193 |
| Heavy Atoms | 18 |
| Complexity | 683.7041 |
Chemical Identifiers
| CAS Number | 844649-61-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)CC2=C(C=CC=C2Cl)Cl |
Product Overview
1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one (CAS 844649-61-2), with molecular formula C12H10Cl2N2O2 and molecular weight 284.01 g/mol. IUPAC: 1-[(2,6-dichlorophenyl)methyl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
Property Insights of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
The XLogP value of 2.20012 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one. With a topological polar surface area (TPSA) of 54.86 Ų, 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one?
The CAS number of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one is 844649-61-2.
What is the molecular formula of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one?
The molecular formula of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one is C12H10Cl2N2O2.
What is the molecular weight of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one?
The molecular weight of 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one is 284.01 g/mol.
Where can I buy 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one?
You can request a quote for 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(2,6-dichlorobenzyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.