![(5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one structure](/static/products/843/843669-69-2.png)
(5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one
TL;DR: (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one (CAS 843669-69-2) is a chemical compound with molecular formula C25H26F3N3OS and molecular weight 473.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one, (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one, (E)-5-(4-(tert-butyl)benzylidene)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)thiazol-4(5H)-one
| Molecular Formula | C25H26F3N3OS |
|---|---|
| Molecular Weight | 473.17 g/mol |
| LogP | 5.7954 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 473.17487 |
| Heavy Atoms | 33 |
| Complexity | 1093.1156 |
Chemical Identifiers
| CAS Number | 843669-69-2 |
|---|---|
| SMILES | CC(C)(C)C1=CC=C(C=C1)/C=C/2\C(=O)N=C(S2)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F |
Product Overview
(5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one (CAS 843669-69-2), with molecular formula C25H26F3N3OS and molecular weight 473.17 g/mol. IUPAC: (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one
Property Insights of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one
The XLogP value of 5.7954 indicates that (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.91 Ų, (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one?
The CAS number of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one is 843669-69-2.
What is the molecular formula of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one?
The molecular formula of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one is C25H26F3N3OS.
What is the molecular weight of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one?
The molecular weight of (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one is 473.17 g/mol.
Where can I buy (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one?
You can request a quote for (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-(4-tert-butylbenzylidene)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.