(Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide
TL;DR: (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide (CAS 843629-37-8) is a chemical compound with molecular formula C23H27BrN6O2 and molecular weight 498.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[5-bromo-2-hydroxy-1-[(4-methylpiperazin-1-yl)methyl]indol-3-yl]imino-4-(dimethylamino)benzamide
Also Known As: (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide, N'-{(3Z)-5-bromo-1-[(4-methylpiperazin-1-yl)methyl]-2-oxo-1,2-dihydro-3H-indol-3-ylidene}-4-(dimethylamino)benzohydrazide, N-[(E)-[5-bromo-1-[(4-methylpiperazin-1-yl)methyl]-2-oxoindol-3-ylidene]amino]-4-(dimethylamino)benzamide, N-[[5-bromo-1-[(4-methylpiperazin-1-yl)methyl]-2-oxoindol-3-ylidene]amino]-4-(dimethylamino)benzamide
| Molecular Formula | C23H27BrN6O2 |
|---|---|
| Molecular Weight | 498.14 g/mol |
| LogP | 4.3044 |
| Topological Polar Surface Area | 76.67 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 498.13788 |
| Heavy Atoms | 32 |
| Complexity | 1147.4982 |
Chemical Identifiers
| CAS Number | 843629-37-8 |
|---|---|
| SMILES | CN1CCN(CC1)CN2C3=C(C=C(C=C3)Br)C(=C2O)N=NC(=O)C4=CC=C(C=C4)N(C)C |
Product Overview
(Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide (CAS 843629-37-8), with molecular formula C23H27BrN6O2 and molecular weight 498.14 g/mol. IUPAC: N-[5-bromo-2-hydroxy-1-[(4-methylpiperazin-1-yl)methyl]indol-3-yl]imino-4-(dimethylamino)benzamide.
Chemical Property Profile of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide
Property Insights of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide
The XLogP value of 4.3044 indicates that (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.67 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide. Following Lipinski's Rule of Five, (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide?
The CAS number of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide is 843629-37-8.
What is the molecular formula of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide?
The molecular formula of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide is C23H27BrN6O2.
What is the molecular weight of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide?
The molecular weight of (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide is 498.14 g/mol.
Where can I buy (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide?
You can request a quote for (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N'-(5-bromo-1-((4-methylpiperazin-1-yl)methyl)-2-oxoindolin-3-ylidene)-4-(dimethylamino)benzohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.