(Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
TL;DR: (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one (CAS 840477-06-7) is a chemical compound with molecular formula C14H7ClFNOS3 and molecular weight 354.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-3-(3-chloro-4-fluorophenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-4-one
Also Known As: (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one, (5Z)-3-(3-chloro-4-fluorophenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-4-one
| Molecular Formula | C14H7ClFNOS3 |
|---|---|
| Molecular Weight | 354.94 g/mol |
| LogP | 4.9464 |
| Topological Polar Surface Area | 20.31 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 354.93622 |
| Heavy Atoms | 21 |
| Complexity | 757.58453 |
Chemical Identifiers
| CAS Number | 840477-06-7 |
|---|---|
| SMILES | C1=CSC(=C1)/C=C\2/C(=O)N(C(=S)S2)C3=CC(=C(C=C3)F)Cl |
Product Overview
(Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one (CAS 840477-06-7), with molecular formula C14H7ClFNOS3 and molecular weight 354.94 g/mol. IUPAC: (5Z)-3-(3-chloro-4-fluorophenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-4-one.
Chemical Property Profile of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
Property Insights of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
The XLogP value of 4.9464 indicates that (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.31 Ų, (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one?
The CAS number of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one is 840477-06-7.
What is the molecular formula of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one?
The molecular formula of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one is C14H7ClFNOS3.
What is the molecular weight of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one?
The molecular weight of (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one is 354.94 g/mol.
Where can I buy (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one?
You can request a quote for (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-3-(3-chloro-4-fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.