Domperidone Maleate structure

Domperidone Maleate

TL;DR: Domperidone Maleate (CAS 83898-65-1) is a chemical compound with molecular formula C26H28ClN5O6 and molecular weight 541.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

but-2-enedioic acid;6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one

Also Known As: Domperidone Maleate, Apo Domperidone, Motilium 10, Domperidone (maleate), Domperidone (monomaleate)

CAS: 83898-65-1
Molecular Formula C26H28ClN5O6
Molecular Weight 541.17 g/mol
LogP 3.065
Topological Polar Surface Area 143.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 541.1728
Heavy Atoms 38
Complexity 774.0

Chemical Identifiers

CAS Number 83898-65-1
SMILES C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O.C(=CC(=O)O)C(=O)O
InChIKey OAUUYDZHCOULIO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (80 patents)

Product Overview

Domperidone Maleate (CAS 83898-65-1), with molecular formula C26H28ClN5O6 and molecular weight 541.17 g/mol. IUPAC: but-2-enedioic acid;6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Domperidone Maleate

XLogP
3.065
TPSA (Topological Polar Surface Area)
143.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
38
Complexity
774.0
Exact Mass
541.1728
Monoisotopic Mass
541.1728
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Domperidone Maleate

The XLogP value of 3.065 indicates that Domperidone Maleate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 143.0 Ų indicates high polarity, suggesting Domperidone Maleate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Domperidone Maleate has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Domperidone Maleate?

The CAS number of Domperidone Maleate is 83898-65-1.

What is the molecular formula of Domperidone Maleate?

The molecular formula of Domperidone Maleate is C26H28ClN5O6.

What is the molecular weight of Domperidone Maleate?

The molecular weight of Domperidone Maleate is 541.17 g/mol.

Where can I buy Domperidone Maleate?

You can request a quote for Domperidone Maleate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Domperidone Maleate?

Yes, KEHONG BIO provides custom synthesis services for Domperidone Maleate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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