4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol
TL;DR: 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol (CAS 83863-40-5) is a chemical compound with molecular formula C18H21NO3S and molecular weight 331.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-ol
Also Known As: 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol, 1-[(4-methylphenyl)sulfonyl]-4-phenylpiperidin-4-ol, 4-phenyl-1-(p-tolylsulfonyl)piperidin-4-ol, 1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-ol, 1-[(4-methylbenzene)sulfonyl]-4-phenylpiperidin-4-ol
| Molecular Formula | C18H21NO3S |
|---|---|
| Molecular Weight | 331.12 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 66.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 331.1242 |
| Heavy Atoms | 23 |
| Complexity | 477.0 |
Chemical Identifiers
| CAS Number | 83863-40-5 |
|---|---|
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)N2CCC(CC2)(C3=CC=CC=C3)O |
| InChIKey | HXIDISDSNWNESD-UHFFFAOYSA-N |
Product Overview
4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol (CAS 83863-40-5), with molecular formula C18H21NO3S and molecular weight 331.12 g/mol. IUPAC: 1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-ol.
Chemical Property Profile of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol
Property Insights of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol. The TPSA of 66.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol. Following Lipinski's Rule of Five, 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol?
The CAS number of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol is 83863-40-5.
What is the molecular formula of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol?
The molecular formula of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol is C18H21NO3S.
What is the molecular weight of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol?
The molecular weight of 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol is 331.12 g/mol.
Where can I buy 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol?
You can request a quote for 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 4-Phenyl-1-(p-tolylsulphonyl)piperidin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.