![1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine structure](/static/products/837/837385-24-7.png)
1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine
TL;DR: 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine (CAS 837385-24-7) is a chemical compound with molecular formula C20H18FN3OS and molecular weight 367.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazin-1-yl]-phenylmethanone
Also Known As: ASN 06587933, 1-benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine, AO-080/43441741, [4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazin-1-yl]-phenylmethanone, {4-[4-(4-Fluoro-phenyl)-thiazol-2-yl]-piperazin-1-yl}-phenyl-methanone
| Molecular Formula | C20H18FN3OS |
|---|---|
| Molecular Weight | 367.12 g/mol |
| LogP | 3.9116 |
| Topological Polar Surface Area | 36.44 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 367.11545 |
| Heavy Atoms | 26 |
| Complexity | 886.93445 |
Chemical Identifiers
| CAS Number | 837385-24-7 |
|---|---|
| SMILES | C1CN(CCN1C2=NC(=CS2)C3=CC=C(C=C3)F)C(=O)C4=CC=CC=C4 |
Product Overview
1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine (CAS 837385-24-7), with molecular formula C20H18FN3OS and molecular weight 367.12 g/mol. IUPAC: [4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazin-1-yl]-phenylmethanone.
Chemical Property Profile of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine
Property Insights of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine
The XLogP value of 3.9116 indicates that 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.44 Ų, 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine?
The CAS number of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine is 837385-24-7.
What is the molecular formula of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine?
The molecular formula of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine is C20H18FN3OS.
What is the molecular weight of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine?
The molecular weight of 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine is 367.12 g/mol.
Where can I buy 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine?
You can request a quote for 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-Benzoyl-4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.