Mitomycin C derivative structure

Mitomycin C derivative

TL;DR: Mitomycin C derivative (CAS 83586-86-1) is a chemical compound with molecular formula C17H23N5O5 and molecular weight 377.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(4R,6R,7S,8R)-11-(2-aminoethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

Also Known As: Mitomycin C derivative, MITOMYCIN C DERIV, [(4R,6R,7S,8R)-11-(2-aminoethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate, {(1aR,8R,8aS,8bR)-6-[(2-Aminoethyl)amino]-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl}methyl carbamate, Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-6-[(2-aminoethyl)amino]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aR-(1a.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-

CAS: 83586-86-1
Molecular Formula C17H23N5O5
Molecular Weight 377.17 g/mol
LogP -1.2
Topological Polar Surface Area 159.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 9
Rotatable Bonds 7
Exact Mass 377.16992
Heavy Atoms 27
Complexity 806.0

Chemical Identifiers

CAS Number 83586-86-1
SMILES CC1=C(C(=O)C2=C(C1=O)N3C[C@@H]4[C@H]([C@]3([C@H]2COC(=O)N)OC)N4)NCCN
InChIKey HMHSJFSMMBIHNN-KPHSQFCKSA-N

Product Overview

Mitomycin C derivative (CAS 83586-86-1), with molecular formula C17H23N5O5 and molecular weight 377.17 g/mol. IUPAC: [(4R,6R,7S,8R)-11-(2-aminoethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Mitomycin C derivative

XLogP
-1.2
TPSA (Topological Polar Surface Area)
159.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
9
Rotatable Bonds
7
Heavy Atoms
27
Complexity
806.0
Exact Mass
377.16992
Monoisotopic Mass
377.16992
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Mitomycin C derivative

The XLogP value of -1.2 indicates that Mitomycin C derivative is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 159.0 Ų indicates high polarity, suggesting Mitomycin C derivative may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Mitomycin C derivative has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Mitomycin C derivative?

The CAS number of Mitomycin C derivative is 83586-86-1.

What is the molecular formula of Mitomycin C derivative?

The molecular formula of Mitomycin C derivative is C17H23N5O5.

What is the molecular weight of Mitomycin C derivative?

The molecular weight of Mitomycin C derivative is 377.17 g/mol.

Where can I buy Mitomycin C derivative?

You can request a quote for Mitomycin C derivative directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Mitomycin C derivative?

Yes, KEHONG BIO provides custom synthesis services for Mitomycin C derivative and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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