5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
TL;DR: 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one (CAS 83539-34-8) is a chemical compound with molecular formula C15H15ClN2OS and molecular weight 306.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-chlorophenyl)methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
Also Known As: AB00084188-01, 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one, A0852/0039906, (5E)-5-[(4-chlorophenyl)methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one, (5E)-5-[(4-CHLOROPHENYL)METHYLIDENE]-2-(PIPERIDIN-1-YL)-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
| Molecular Formula | C15H15ClN2OS |
|---|---|
| Molecular Weight | 306.06 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 58.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 306.05936 |
| Heavy Atoms | 20 |
| Complexity | 435.0 |
Chemical Identifiers
| CAS Number | 83539-34-8 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=O)/C(=C\C3=CC=C(C=C3)Cl)/S2 |
| InChIKey | JREKHXBULNREND-JLHYYAGUSA-N |
Product Overview
5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one (CAS 83539-34-8), with molecular formula C15H15ClN2OS and molecular weight 306.06 g/mol. IUPAC: (5E)-5-[(4-chlorophenyl)methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one.
Chemical Property Profile of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
Property Insights of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
The XLogP value of 3.9 indicates that 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.0 Ų, 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The CAS number of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is 83539-34-8.
What is the molecular formula of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The molecular formula of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is C15H15ClN2OS.
What is the molecular weight of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The molecular weight of 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is 306.06 g/mol.
Where can I buy 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
You can request a quote for 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-chlorobenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.