Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate structure

Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate

TL;DR: Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate (CAS 83353-97-3) is a chemical compound with molecular formula C21H29ClO3 and molecular weight 364.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl (1R,3R,4aS,10aR)-8-chloro-3-hydroxy-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate

Also Known As: Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate, 1-Phenanthrenecarboxylic acid, 8-chloro-1,2,3,4,4a,9,10,10a-octahydro-3-hydroxy-1,4a-dimethyl-7-(1-methylethyl)-, methyl ester, (1R-(1alpha,3alpha,4abeta,10aalpha))-, Methyl 14-chloro-2alpha-hydroxyabieta-8,11,13-trien-18-oate, methyl (1R,3R,4aS,10aR)-8-chloro-3-hydroxy-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate

CAS: 83353-97-3
Molecular Formula C21H29ClO3
Molecular Weight 364.18 g/mol
LogP 5.2
Topological Polar Surface Area 46.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 3
Exact Mass 364.1805
Heavy Atoms 25
Complexity 521.0

Chemical Identifiers

CAS Number 83353-97-3
SMILES CC(C)C1=C(C2=C(C=C1)[C@]3(C[C@H](C[C@@]([C@@H]3CC2)(C)C(=O)OC)O)C)Cl
InChIKey OCIGNQIZVJGTBR-HYPSKJLKSA-N

Product Overview

Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate (CAS 83353-97-3), with molecular formula C21H29ClO3 and molecular weight 364.18 g/mol. IUPAC: methyl (1R,3R,4aS,10aR)-8-chloro-3-hydroxy-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate

XLogP
5.2
TPSA (Topological Polar Surface Area)
46.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
3
Heavy Atoms
25
Complexity
521.0
Exact Mass
364.1805
Monoisotopic Mass
364.1805
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate

The XLogP value of 5.2 indicates that Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.5 Ų, Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate?

The CAS number of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate is 83353-97-3.

What is the molecular formula of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate?

The molecular formula of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate is C21H29ClO3.

What is the molecular weight of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate?

The molecular weight of Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate is 364.18 g/mol.

Where can I buy Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate?

You can request a quote for Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate?

Yes, KEHONG BIO provides custom synthesis services for Methyl 14-chloro-2-hydroxyabieta-8,11,13-trien-18-oate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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