RefChem:287937
TL;DR: RefChem:287937 (CAS 832673-62-8) is a chemical compound with molecular formula C19H18ClN3OS and molecular weight 371.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-chlorophenyl)-6-methyl-2-methylsulfanyl-N-phenyl-1,4-dihydropyrimidine-5-carboxamide
Also Known As: 4-(4-Chlorophenyl)-1,4-dihydro-6-methyl-2-(methylthio)-N-phenyl-5-pyrimidinecarboxamide, 4-(4-chlorophenyl)-6-methyl-2-methylsulfanyl-N-phenyl-1,4-dihydropyrimidine-5-carboxamide, 6-(4-chlorophenyl)-4-methyl-2-(methylsulfanyl)-N-phenyl-1,6-dihydro-5-pyrimidinecarboxamide, 6-(4-chlorophenyl)-4-methyl-2-(methylsulfanyl)-N-phenyl-1,6-dihydropyrimidine-5-carboxamide, RefChem:287937
| Molecular Formula | C19H18ClN3OS |
|---|---|
| Molecular Weight | 371.09 g/mol |
| LogP | 4.616 |
| Topological Polar Surface Area | 53.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 371.0859 |
| Heavy Atoms | 25 |
| Complexity | 831.5075 |
Chemical Identifiers
| CAS Number | 832673-62-8 |
|---|---|
| SMILES | CC1=C(C(N=C(N1)SC)C2=CC=C(C=C2)Cl)C(=O)NC3=CC=CC=C3 |
Product Overview
RefChem:287937 (CAS 832673-62-8), with molecular formula C19H18ClN3OS and molecular weight 371.09 g/mol. IUPAC: 4-(4-chlorophenyl)-6-methyl-2-methylsulfanyl-N-phenyl-1,4-dihydropyrimidine-5-carboxamide.
Chemical Property Profile of RefChem:287937
Property Insights of RefChem:287937
The XLogP value of 4.616 indicates that RefChem:287937 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.49 Ų, RefChem:287937 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:287937 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:287937?
The CAS number of RefChem:287937 is 832673-62-8.
What is the molecular formula of RefChem:287937?
The molecular formula of RefChem:287937 is C19H18ClN3OS.
What is the molecular weight of RefChem:287937?
The molecular weight of RefChem:287937 is 371.09 g/mol.
Where can I buy RefChem:287937?
You can request a quote for RefChem:287937 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:287937?
Yes, KEHONG BIO provides custom synthesis services for RefChem:287937 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.